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In addition to confirming that bacteria in root canals do not exist in free-floating planktonic states as previously assumed, this new information on root canal biofilm infections has provided an opportunity to re-evaluate conventional clinical protocols and improve endodontic therapeutic measures.
The Biofilm Primer.
View of Biofilms in the ICU | The Southwest Respiratory and Critical Care Chronicles
Book 1. This book details the widely accepted hypothesis that the majority of bacteria in virtually all ecosystems grow in matrix-enclosed biofilms. The author, who first proposed this biofilm hypothesis, uses direct evidence from microscopy and from molecular techniques, arguing cogently for moving beyond conventional culture methods that dominated microbiology in the last century. Bacteria grow predominantly in biofilms in natural, engineered, and pathogenic ecosystems; this book provides a solid basis for the understanding of bacterial processes in environmental, industrial, agricultural, dental and medical microbiology.
Using a unique "ecological" perspective, the author explores the commensal and pathogenic colonization of human organ systems. Control of Biofilm Infections by Signal Manipulation. Book 2.
As one convocation follows another, and as our funding agencies pump billions of dollars into incremental research that? It is this small band of nimble and impossibly brave intellectual halfbackswho win gamesin the real world, and this book is the result of the drive and intellectual athleticism of its editor and several of her contributors.
Bacteria affect humans more than any other life forms with which we share the blue planet, but our understandingof these invisible companionshas developed in a staggering pattern, crippled by our panic and consequent shifts of emphasis.
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- From Diagnosis to Treatment and Prevention;
When our race was threatened by epidemic diseases, we visualized bacteria as swarms of potentially lethal planktoniccells from which we must remain isolated by sanitation and which we had to kill by immunization and chemical antibacterial compounds. By the time this overriding threat had been obviated, we began to examine na- ral and pathogenic ecosystems by direct methods, and we were surprised to?
Book 3. Since the use and the types of indwelling medical devices commonly used in modern healthcare are continuously expanding, especially with an aging population, the incidence of biofilm infections will also continue to rise.
The central problem with microbial biofilm infections of foreign bodies is their propensity to resist clearance by the host immune system and all antimicrobial agents tested to date. In fact, compared to their free floating, planktonic counterparts, microbes within a biofilm are 50 — times more resistant to antimicrobial agents. Therefore, achieving therapeutic and non-lethal dosing regimens within the human host is impossible. The end result is a conversion from an acute infection to one that is persistent, chronic, and recurrent, most often requiring device removal in order to eliminate the infection.
This text will describe the major types of device-related infections, and will explain the host, pathogen, and the unique properties of their interactions in order to gain a better understanding of these recalcitrant infections. Marine and Industrial Biofouling. Book 4. Biofouling is a costly problem, and it is encountered in a wide spectrum of technical systems, ranging from the shipping industry, power industry, water purification, automobile industry, paint and pharmaceuticals, to the microelectronics and food industries.
Micro- and macroorganisms attach to surfaces and accumulate there, forming biofilms that cause interferences — a fundamentally natural process. Usually, a medical paradigm is applied: kill biofilms and the problem is solved. This leads to excessive biocide use. However, the success of this strategy is very limited; furthermore it leads to equipment damage and environmental pollution.
Simply trying to kill the fouling organisms is clearly not seen as a successful strategy while cleaning is put forward as much more important. In this book, strategies to prevent adhesion, to mitigate the extent and effects of biofouling, and to detect and remove fouling layers are presented.
Holistic approaches to the fouling process are elaborated, taking into account options such as nutrient limitation, repellent and easy-to-clean surfaces for fouling layer limitation, and replacing biocides with more environmentally friendly methods — in other words: learning how to live with fouling biofilms without suffering the damage they can do. More related to microbiology. Microbiology for Clinicians. A practising clinician is required to use knowledge from many differ ent fields.
It is unrealistic to expect him to be master of more than a few. In reality, clinicians acquire a smattering of information on most relevant subjects, and learn which texts provide the detailed informa tion which is occasionally required on more highly specialized matters. In my professional contacts with clinicians and medical students it has become evident that they often lack the simple frame work of microbiological knowledge necessary to guide their actions.
This is because standard textbooks and learned treatises alike are con cerned with imparting a body of information rather than with present ing what the doctor needs to know in order to manage his patients. This volume is an attempt to help clinicians in their everyday practice.
To that end I have kept it short and have not dwelt at length even on those topics which especially interest me. No attempt has been made to write a textbook: many of these already exist. A few refer ences are given to major reviews and to sources justifying some of the more forthright statements. The subject of medical microbiology is broad and involved.
I have therefore seen it as my task to simplify the presentation of the material, being very selective with regard to content and giving my own views on matters of clinical significance. New Weapons to Control Bacterial Growth.
From Diagnosis to Treatment and Prevention
Tomas G. Written by specialists in the different fields, this book presents new perspectives and insights into strategies and weapons to fight microbial infections. In an era of accumulated resistance to current antibiotics, it is vital that this is undertaken without further delay. Aspects discussed include the control of RNA synthesis, the use of bacteriocins or enzybiotics bacteriophages or purified lysins , the specific control of pathogenic clostridia, the design of new drugs affecting DNA synthesis in bacteria, the use of fecal-matter transplant strategies, the specific control of quorum sensing responses in bacteria, the use of new peptides as antibiotics and new ways to control bacteria that cause cancer, such as Helicobacter pylori cancers.
Pulmonary Infection. Book The respiratory tract is a frequent target of infections caused by a wide range of organisms. The book provides reader-friendly information on aspects of pulmonary infections, including comprehensive accounts of bacterial and viral diseases, therapeutic approaches, molecular and classical culture-related techniques of diagnosis and explaining the basic cell biological mechanism.
The role of oxidative stress, both helpful in fighting invading pathogens and detrimental in yielding to infection is detailed as it is often undervalued and needs focus. The chapters encompass latest developments and applications in bacteriology and virology, preventive and therapeutic tips, and raise attention to implementation of proper antibiotic policies by medical institutions to decrease resistance to antimicrobials.
The perennial problem of low influenza vaccination coverage rate is rationalized. The volume will be of interest to both clinicians and biomedical researchers engaged in this exciting field. More than 30 newly emerged microorganisms and related diseases have been discovered in the past 20 years.
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